Presentations
- Cough
- Pain, including:
- Swelling
Conditions
- Arterial thrombosis and paediatric stroke
- Thrombophilia:
- Thrombotic thrombocytopenic purpura (TTP) and thrombosis
- Venous thromboembolism:
For each presentation and condition, Advanced Trainees will know
how
to:
Synthesise
- recognise the clinical presentation
- identify relevant epidemiology, prevalence, pathophysiology, and clinical science
- take a comprehensive clinical history
- conduct an appropriate examination
- establish a differential diagnosis
- plan and arrange appropriate investigations
- consider the impact of illness and disease on patients and their quality of life
when
developing a management plan
Manage
- provide evidence-based management
- prescribe therapies tailored to patients’ needs and conditions
- recognise potential complications of disease and its management, and initiate
preventative strategies
- involve multidisciplinary teams
Consider other factors
- identify individual and social factors and the impact of these on diagnosis and
management
Conditions
- Antiphospholipid syndrome
- Antithrombin III deficiency:
- thrombophilias of minimal significance
- Paroxysmal nocturnal haemoglobinuria
- Protein C and S deficiency, including:
- Vascular malformation
For each presentation and condition, Advanced Trainees will know how to:
Synthesise
- recognise the clinical presentation
- identify relevant epidemiology, prevalence, pathophysiology, and clinical science
- take a comprehensive clinical history
- conduct an appropriate examination
- establish a differential diagnosis
- plan and arrange appropriate investigations
- consider the impact of illness and disease on patients and their quality of life
when
developing a management plan
Manage
- provide evidence-based management
- prescribe therapies tailored to patients’ needs and conditions
- recognise potential complications of disease and its management, and initiate
preventative strategies
- involve multidisciplinary teams
Consider other factors
- identify individual and social factors and the impact of these on diagnosis and
management
- Acquired and inherited risk factors and associations in patients with thromboembolic disease
- Anticoagulant medications:
- appropriate choice of agent
- dosing
- duration of therapy
- mechanism of action
- monitoring reversal
- Complications, diagnostic strategies, natural history, and presentation of inherited and
acquired thrombophilia
- Pathophysiology of arterial and venous thrombosis, including epidemiology and molecular basis of
thrombophilia
- Pathophysiology of vascular anomalies, and how this relates to medical therapies
- Techniques for the measurement of recognised laboratory thrombophilia
- Clinical and laboratory investigation, such as:
- anticoagulant levels
- anticoagulant therapy monitoring
- antiphospholipid antibody testing
- dilute Russell viper venom time screen and confirmation
- lupus anticoagulant testing
- thrombophilia screening and limited indications
- Nuclear medicine, such as:
- ventilation perfusion (VQ) scan
- Radiological investigations, such as:
- CT:
- MRI
- magnetic resonance angiography (MRA)
- magnetic resonance venography (MRV)
- ultrasound, including:
Anti-thrombotic therapy
- Follow-up of patients receiving anticoagulants
- Heparin and oral anticoagulant therapy
- Heparin-induced thrombocytopenia
- Management of over-anticoagulation
- Molecular drivers of vascular malformation, and targeted and novel therapies for vascular
malformations
- Ordering of radiologic investigations, and liaison with other clinical teams
- Perioperative management of patients on antithrombotic therapy
- Risks and benefits, including potential adverse effects
