Curriculum standards
Curriculum standards
Advanced Training in Endocrinology (Adult Internal Medicine)
Knowledge guides
LG 15: Disorders of glucose metabolism
Key presentations and conditions
Advanced Trainees will have a comprehensive depth of knowledge of these presentations and conditions.
Less common or more complex presentations and conditions
Advanced Trainees will understand these presentations and conditions.
Advanced Trainees will understand the resources that should be used to help manage patients with these presentations and conditions.
Epidemiology, pathophysiology, and clinical sciences
Advanced Trainees will have a comprehensive depth of knowledge of the principles of the foundational sciences.
Investigations, procedures, and clinical assessment tools
Advanced Trainees will know the scientific foundation of each investigation and procedure, including relevant anatomy and physiology. They will be able to interpret the reported results of each investigation or procedure.
Advanced Trainees will know how to explain the investigation or procedure to patients, families, and carers, and be able to explain procedural risk and obtain informed consent where applicable.
Important specific issues
Advanced Trainees will identify important specialty-specific issues and the impact of these on diagnosis and management and integrate these into care.
Presentations
- Asymptomatic with detection of hyperglycaemia on screening
- Autonomic disease:
- cardiac
- gastroparesis
- postural hypotension
- sexual dysfunction
- Cognitive decline
- Diabetic amyotrophy
- Diabetes foot disease:
- Charcot arthropathy
- prevention/management of foot ulcers
- Hyperglycaemic metabolic emergencies
- Hypoglycaemia:
- hypoglycaemia unawareness
- medication induced
- postprandial
- Infection, often recurrent or severe
- Macrovascular disease:
- cerebrovascular disease
- ischaemic heart disease
- peripheral vascular disease
- Microvascular disease:
- peripheral neuropathy
- renal nephropathy
- Mood changes
- Polydipsia/Polyuria
- Postprandial fatigue
- Retinopathy
- Visual disturbances
- Weight loss
Conditions
- Diabetes mellitus:
- gestational
- monogenic
- type 1
- type 2
- Diabetes secondary to other conditions:
- cystic fibrosis
- haemochromatosis
- post-transplantation
- pancreatic insufficiency:
- alcoholism
- pancreatectomy
- pancreatic cancer
- recurrent pancreatitis
- Drug induced diabetes, including steroid-induced and antipsychotic-induced
- Hyperinsulinaemica
- Hypoglycaemia
- Latent autoimmune diabetes adult (LADA)
- Mild age-related diabetes (MARD)
- Mild obesity-related diabetes (MOD)
- Prediabetes
- Severe insulin deficiency (SIDD)
- Severe insulin resistance (SIRD)
For each presentation and condition, Advanced Trainees will know how to:
Synthesise
- recognise the clinical presentation
- identify relevant epidemiology, prevalence, pathophysiology, and clinical science
- take a comprehensive clinical history
- conduct an appropriate examination
- establish a differential diagnosis
- plan and arrange appropriate investigations
- consider the impact of illness and disease on patients and their quality of life when developing a management plan
Manage
- provide evidence-based management
- prescribe therapies tailored to patients' needs and conditions
- recognise potential complications of disease and its management, and initiate preventative strategies
- involve multidisciplinary teams
Consider other factors
- identify individual and social factors and the impact of these on diagnosis and management
Conditions
- Pancreatic transplant or islet cell transplant indications and management
- Rare syndromes associated with increased diabetes risk
For each presentation and condition, Advanced Trainees will know how to:
Synthesise
- recognise the clinical presentation
- identify relevant epidemiology, prevalence, pathophysiology, and clinical science
- take a comprehensive clinical history
- conduct an appropriate examination
- establish a differential diagnosis
- plan and arrange appropriate investigations
- consider the impact of illness and disease on patients and their quality of life when developing a management plan
Manage
- provide evidence-based management
- prescribe therapies tailored to patients' needs and conditions
- recognise potential complications of disease and its management, and initiate preventative strategies
- involve multidisciplinary teams
Consider other factors
- identify individual and social factors and the impact of these on diagnosis and management
Diabetes
Insulin dose adjustments (irrespective of insulin delivery method)
- Safe dose adjustment in response to:
- alcohol and recreational drug use
- blood glucose levels
- concurrent treatments that impact blood glucose (e.g. glucocorticoids and parenteral nutrition etc.)
- exercise
- intravenous insulin regimens:
- dosing
- indications
- initiation
- transition to subcutaneous
- nutrition and fasting
- peri-operative and peri-procedures
- pregnancy, lactation, labour, and postpartum
- sick days
- titration
Lifestyle management
- Counselling and best evidence-based lifestyle advice for individuals to prevent the development of Type 2 diabetes or to manage all forms of established diabetes:
- alcohol, recreational drugs, smoking, and vaping
- carbohydrate counting
- contraception and pre-conception planning, management during pregnancy and postpartum
- education and employment
- nutrition and diet
- physical activity and reducing sedentariness
- weight management
Pharmacological management
- Apply up to date, evidence-based best practice and clinical judgement to individualised medication management plans
- Action profiles of various insulins and combination regimens:
- effects of concurrent drug therapies on glycaemia
- evidence-based use of pharmacotherapy for non-glycaemic benefits in diabetes populations, e.g. cardiovascular or renal benefits
- Knowledge of the pharmacological therapy indicated for:
- gestational diabetes mellitus
- MODY
- pancreatectomy or endocrine pancreatic insufficiency
- type 1 diabetes mellitus and LADA
- type 2 diabetes mellitus
- Mechanism of action of major non-insulin drug classes in glycaemia
- Principles of pharmacology:
- drug distribution, metabolism, and excretion
- drug interactions, precautions, and contraindications
Screening
- Depression, accelerated cognitive decline, and dementia
- Diabetes complications screening (incorporating allied health and other health professionals wherever indicated) at appropriate intervals for microvascular and macrovascular disease burden
- Diabetes distress, particularly for people living with type 1 or LADA diabetes
- Diagnostic criteria
- Hypertension and dyslipidemia
- Individualised glycaemic targets determined by:
- complications and comorbidities profile
- duration of disease
- goals
- hypoglycaemia risk
- patient preferences
- Metabolic syndrome and associated fatty liver disease (MAFLD)
- Monitoring glycaemia
- Obstructive sleep apnoea (OSA)
- Referral and use of allied health and multidisciplinary professionals in providing holistic team care
- Screening and managing referrals for associated conditions
- Screening for other autoimmune conditions, such as:
- Addison's disease
- coeliac disease
- pernicious anaemia
- thyroid dysfunction
Hyperglycaemic emergencies
- Diabetic ketoacidosis
- Hyperglycaemic hyperosmolar state
Hypoglycaemia
- Acute and preventive management of hypoglycaemia
- Acute hypoglycaemic emergencies
- Investigations and work up of hypoglycaemia in non-diabetes cases
- Mechanisms and associated diseases, including insulinoma, dumping syndrome, nesidioblastosis, post-bariatric surgery
- Recognition and management of hypoglycaemia unawareness
Euglycaemic diabetic ketoacidosis
- Pregnancy-induced
- SGLT2i-induced
- Starvation
- Type 1 diabetes
Diabetes
Advanced technology and devices
- Blood glucose monitoring systems:
- benefits, limitations, and data interpretation (time in range, GMI)
- bolus calculators for multiple daily injection (MDI)
- continuous glucose monitoring (CGM) systems:
- used with MDI therapy and insulin pumps
- principles, benefits, and limitations of closed loop technology
- glucose data interpretation (self-monitored blood glucose readings, continuous glucose monitoring)
- finger prick meters – glucose and ketones
- Calculation and adjustment of:
- basal insulin dose/ratios
- carbohydrate ratio
- insulin sensitivity factor
- Indications and suitability of CSII converting insulin doses from MDI to CSII
- Insulin delivery devices:
- insulin pen devices for MDI therapy
- insulin pumps and features/functions
- Interpretation of insulin pump data
- Principles of continuous subcutaneous insulin infusion (CSII, ‘insulin pump’) therapy, such as:
- basal infusion rates
- pump specific attributes including suspend and exercise
Cardiovascular risk mitigation
- Blood pressure:
- individualised target setting
- investigation for underlying secondary causes of hypertension where appropriate
- monitoring including home, clinic, and 24-hour ambulatory monitoring
- Clinical assessment and comprehensive diabetes physical examination
- Impact of alcohol on diabetes monitoring and management
- Lipid management and targets in diabetes cohort
- Smoking cessation/avoidance
- Weight management
Hypoglycaemia
- Dynamic tests – indications, performing tests, and interpretation:
- mixed-meal test
- 72-hour fast
Investigations
- Gastric emptying study
- Genetic screening:
- rare or suspected inherited forms of diabetes
- Endogenous insulin reserves (when indicated), e.g. paired C-peptide and glucose
- Limitations and interferences in pathology results, such as:
- fructosamine
- HBA1c
- lipid studies
- Nerve conduction studies
- Pancreatic autoimmunity (when indicated or suspected)
- Urine albumin/creatinine ratio
- Use of decision support tools to facilitate clinical decisions such as cardiovascular disease calculator
Evidence based clinical practice
- Beta cell transplantation, including whole pancreas or islet cell transplantation
- Evidence for best practice (e.g., AnnADA guidelines supplement, diabetes care) and application of this using clinical judgement and individual circumstances in partnership with patients
- Fitness to drive according to guidelines
General management considerations
- Educate, support, and empower people to self-manage their diabetes
- Environmentally sustainable practices in clinical care
- Impact of:
- cultural, health literacy, social, geographic and financial barriers to accessing comprehensive diabetes care
- diagnosis of diabetes and of living with diabetes on an individual, their family, their life, and their life stages
- hypoglycaemia unawareness on patients, their family, and carers
- socioeconomic determinants of health on health outcomes
- Equitable access to comprehensive diabetes care delivery for individuals, such as:
- appropriate multicultural resources
- including multidisciplinary involvement
- use of telehealth and other digital health tools
- Recognise the impact of management in the presence of comorbidities including:
- atherosclerotic
- cardiac failure
- chronic kidney disease
- cognitive decline
- obesity
- seizure disorders
Health needs of specific groups
-
Diabetes in youth:
- common risk-taking behaviour in young people and its effects on diabetes
- impact of practitioner’s behaviour on young people
- physiological, psychological and social factors affecting glycaemic levels in adolescence
- potentially negative effects of adolescent behaviour on diabetes and the impact it may have on family and personal relationships
- young people transitioning from paediatric to adult diabetes care
-
Older people and people living with significant disability or life-limiting comorbid conditions:
- adjust management and therapeutic targets based on individual needs and the principles of hypoglycaemia harm mitigation
- ensure careful utilisation of health service resources
- potential effects of these comorbidities on diabetes treatments and glycaemia
- specific social and medical needs of people with diabetes living in residential/nursing care, and those with neurological or cognitive disabilities including additional levels of supervision to ensure safety
- work with multidisciplinary teams and family members who can support people living in the community
-
Management of glycaemia:
- for people with type 1 or LADA diabetes, manage insulin delivery and insulin pump therapy in all stages of pregnancy, in labour and postpartum
- indications and safety of medication use prior to conception, in pregnancy and with lactation
- monitoring advice
- nutrition and exercise advice
- Pre-conception, pregnancy, and lactation
- gestational diabetes:
- diagnostic criteria and screening strategies, including progression of complications
- glycaemic, blood pressure and weight management goals prior to and throughout pregnancy
- impact of intercurrent illness and events on glycaemia, such as administration of glucocorticoids, and how to adjust insulin doses in these situations
- monitor for risks, including progression of maternal complications on fetal development and growth
- recognise the need for pre-pregnancy assessment, counselling, and family planning in women of reproductive age
- gestational diabetes:
- Recognise concerns and anxieties of parents and carers