Presentations
- Abnormalities detected on antenatal blood tests or imaging
- Haematological disorders:
- anaemia
- bleeding
- decreased or increased white cells
- polycythaemia
- thrombocytopenia
- thrombocytosis
- thrombosis
- Neonatal tumours and malignancies
Conditions
- Disorders of platelets and coagulations
- Disorders of white cells
- Haemolysis
- Hypoproduction
- Leukaemias
- Neonatal anaemia
- Neonatal polycythaemia
For each presentation and condition, Advanced Trainees will know how to:
Synthesise
- recognise the clinical presentation
- identify relevant epidemiology, prevalence, pathophysiology, and clinical science
- take a comprehensive clinical history
- conduct an appropriate examination
- establish a differential diagnosis
- plan and arrange appropriate investigations
- consider the impact of illness and disease on patients and their quality of life when
developing a management plan
Manage
- provide evidence-based management
- prescribe therapies tailored to patients’ needs and conditions
- recognise potential complications of disease and its management, and initiate
preventative strategies
- involve multidisciplinary teams
Consider other factors
- identify individual and social factors and the impact of these on diagnosis and
management
Presentations
- Malignancies
- Polycythaemia
Conditions
- Genetic conditions associated with malignancy
- Neonatal tumours and malignancies
- Solid tumours
- Uncommon congenital causes of anaemia, such as:
- congenital dyserythropoietic anaemia (CDA)
- other genetic causes of anaemia
For each presentation and condition, Advanced Trainees will know how to:
Synthesise
- recognise the clinical presentation
- identify relevant epidemiology, prevalence, pathophysiology, and clinical science
- take a comprehensive clinical history
- conduct an appropriate examination
- establish a differential diagnosis
- plan and arrange appropriate investigations
- consider the impact of illness and disease on patients and their quality of life when
developing a management plan
Manage
- provide evidence-based management
- prescribe therapies tailored to patients’ needs and conditions
- recognise potential complications of disease and its management, and initiate
preventative strategies
- involve multidisciplinary teams
Consider other factors
- identify individual and social factors and the impact of these on diagnosis and
management
- Anaemia
- Disorders of coagulation:
- disseminated intravascular coagulation (DIC)
- haemorrhagic disease of the newborn
- neonatal stroke
- thrombocytopaenia
- vascular malformations
- Haemolysis
- Hypoproduction
- Iron transfer in the fetus
- Pathophysiology and management of immune and non-immune neonatal haemolytic diseases
- Pathophysiology of anaemia of prematurity
- Physiology of red cell production and mechanisms of anaemia
- Platelet disorder
- Polycythaemia
- Transfusions and component therapy
- White cell disorders
Investigations
- B12 and folate
- Blood group
- Coagulation studies
- Ferritin
- Full blood counts and films
- Interpretation of blood counts and other tests related to haematological disorders
- Red cell and platelet antigen tests
Procedures
- Bone marrow biopsy and lumbar puncture as investigations of leukaemia
- Exchange transfusion
- Use of blood products and haematinic agents
- Vitamin K prophylaxis
- Medicolegal and ethical considerations in the use of blood products
- Prevention of iatrogenic contributors to anaemia
